1Department of Pediatrics A, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Tel Hashomer 5262000, Israel2Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel3The Center for Geographic Medicine and Tropical Diseases, Sheba Medical Center, Ramat Gan, Tel Hashomer 5262000, Israel