Bactericidal activity of catechin-copper (II) complexes on Escherichia coli ATCC11775 in the absence of hydrogen peroxide

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Washed Escherichia coli ATCC11775 cells were killed by (−)-epigallocatechin (EGC) in the presence of a non-lethal concentration of Cu2+ (1 μmol l−1) without additional H2O2, but not by (−)-epicatechin (EC). EGC alone (< 0.1 mmol l−1) did not reduce the viability of the cells. The survival curve obtained in the presence of EGC and Cu2+ was similar to that obtained in the presence of (−)-adrenaline (EN) and Cu2+.

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