1 Department of Cell Biology and Histology, Institute of Medical Biology, University of Tromsø, Tromsø, Norway2 Centre for Education and Research on Ageing, University of Sydney and Concord RG Hospital, Sydney, NSW, Australia3 Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan4 Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS, USA5 Department of Hepatology, Graduate School of Medicine, Osaka City University, Osaka, Japan6 Department of Cellular Function, Division of Cellular and Molecular Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan7 Institute for Molecular Medicine and Experimental Immunology, Friedrich-Wilhelms-University Bonn, Bonn, Germany8 Department of Nutrition, Case Western Reserve University, Cleveland, OH, USA9 Department of Cell Biology and Histology, Akita University School of Medicine, Akita, Japan10 Department of Cellular Biology and Histology, Basque Country University School of Medicine, Bizkaia, Spain
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This review aims to give an update of the field of the hepatic sinusoid, supported by references to presentations given at the 14th International Symposium on Cells of the Hepatic Sinusoid (ISCHS2008), which was held in Tromsø, Norway, August 31-September 4, 2008. The subtitle of the symposium, ‘Integrating basic and clinical hepatology’, signified the inclusion of both basal and applied clinical results of importance in the field of liver sinusoidal physiology and pathophysiology. Of nearly 50 oral presentations, nine were invited tutorial lectures. The authors of the review have avoided writing a ‘flat summary’ of the presentations given at ISCHS2008, and instead focused on important novel information. The tutorial presentations have served as a particularly important basis in the preparation of this update. In this review, we have also included references to recent literature that may not have been covered by the ISCHS2008 programme. The sections of this review reflect the scientific programme of the symposium (http://www.ub.uit.no/munin/bitstream/10037/1654/1/book.pdf):1. Liver sinusoidal endothelial cells.2. Kupffer cells.3. Hepatic stellate cells.4. Immunology.5. Tumor/metastasis.Symposium abstracts are refered to by a number preceded by the letter A.