An integrable chain connected to the isospectral evolution of the polynomials of type R–I introduced by Ismail and Masson is presented. The equations of motion of this chain generalize the corresponding equations of the relativistic Toda chain introduced by Ruijsenaars. We study simple self-similar solutions to these equations that are obtained through separation of variables. The corresponding polynomials are expressed in terms of the Gauss hypergeometric function. It is shown that these polynomials are stable (up to shifts of the parameters) against Darboux transformations of the generalized chain.