Evaluation of the Safety and Efficacy of the Picosecond Alexandrite Laser With Specialized Lens Array for Treatment of the Photoaging DéColletage

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Abstract

Background:

Fractionated lasers are routinely used to treat the characteristic cutaneous signs of photoaging. In this study, we evaluate the use of picosecond pulse duration combined with a diffractive lens array for treatment of photodamage of the décolletage.

Methods:

Twenty subjects with Fitzpatrick skin types I–IV were enrolled in a prospective open-label trial evaluating the efficacy of the 755 nm picosecond pulsed alexandrite laser with diffractive lens array for treatment of photodamage to the décolletage. Each subject received a series of four laser treatments at 3 week intervals. Follow up evaluation was performed 1 and 3 months later by a masked investigator and consisted of assessment of dyspigmentation, erythema, keratosis, texture, and rhytides on a standardized 5 point scale; global aesthetic improvement 5 point scale; and investigator and subject satisfaction questionnaire. Adverse events and treatment discomfort was also assessed.

Results:

Statistically significant improvement in dyspigmentation, keratosis, and skin texture were observed at both 1 and 3 month follow up intervals (P < 0.05). rhytides initially demonstrated significant improvement at the 1 month time point, but this significance was not maintained at 3 months (P = 0.08). There was no statistically significant improvement noted in erythema. The majority of subjects were satisfied, with a mean rating of 2.8/6 (one being extremely satisfied and six being extremely dissatisfied). Subject pain was 3.6/10.

Conclusion:

The 755 nm picosecond pulsed alexandrite laser with diffractive lens array can be an effective option for rejuvenation of the photodamaged décolletage. Lasers Surg. Med. 48:188–192, 2016. © 2015 Wiley Periodicals, Inc.

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