|| Checking for direct PDF access through Ovid
To achieve high-quality unilateral supine breast magnetic resonance imaging (MRI) as a step to facilitate image aiding of clinical applications, which are often performed in the supine position. Contrast-enhanced breast MRI is a powerful tool for the diagnosis of cancer. However, prone patient positioning typically used for breast MRI hinders its use for image aiding.A fixture and a flexible four-element receive coil were designed for patient-specific shaping and placement of the coil in close conformity to the supine breast. A 3D spoiled gradient sequence was modified to incorporate compensation of respiratory motion. The entire setup was tested in volunteer experiments and in a pilot patient study.The flexible coil design and the motion compensation produced supine breast MR images of high diagnostic value. Variations in breast shape and in tissue morphology within the breast were observed between a supine and a diagnostic prone MRI of a patient.The presented supine breast MRI achieved an image quality comparable to diagnostic breast MRI. Since supine positioning is common in many clinical applications such as ultrasound-guided breast biopsy or breast-conserving surgery, the registration of the supine images will aid these applications. J. Magn. Reson. Imaging 2011;. © 2011 Wiley Periodicals, Inc.