A thermal dysregulation problem after breast cancer surgery; what could be?

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Chronic fatigue syndrome (CFS) is a complicated disorder characterized by severe fatigue that is not relieved with rest and associated with physical symptoms such as sleep problems, headache, muscle pain, or joint pain.

Patient concerns:

Forty-one year old patient complained from feeling cold after breast cancer surgery.


The diagnoses of fibromyalgia, depression, neurological, psychiatric, and vascular disorders were excluded by appropriate clinical and laboratory investigations. She was diagnosed as CFS.


The patient was treated successfully via aerobic exercise therapy that scheduled for 30 min at least 3 days per week.


At 6-month follow-up, her complaints were almost resolved and the patient regained her physical health and mental attitude.


A thermal dysregulation should be taken into consideration as one of the symptoms of CFS.

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