Sclerosing thymoma: A rare case report and brief review of literature

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Abstract

Rationale:

Sclerosing thymoma is an extremely rare mediastinal neoplasm; it was recognized for the first time in 1994 and to date only 15 cases have been reported.

Patient concerns:

The present study report a case of a 65-year-old man who was incidentally found to have an anterior mediastinal nodule, without clinical symptoms including fever, chest pain, and myasthenia gravis.

Diagnoses:

The chest computed tomography (CT) revealed the nodule was 4.9 × 4.2 × 3.0 cm in size. And the microscopic and immunohistochemical findings indicated that the final diagnosis was sclerosing thymoma.

Interventions:

The anterior mediastinal nodule was completely removed.

Outcomes:

No evidence of recurrence or complication was found in the second year after surgery.

Lessons:

The biologic behavior of the rare sclerosing thymoma is still largely mysterious; it is utmost importance to classify the sclerosing thymoma from other mediastinal tumors. Its prognosis is favorable and thymectomy is currently the mainstay of treatment.

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