Intracranial hemorrhage associated with medulla oblongata dysplasia in a premature infant: A case report

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Rationale:Medulla oblongata dysplasia is an extremely rare form of neurodevelopmental immaturity in premature infants. Intracranial hemorrhage in premature infants may be closely related to neurodevelopmental immaturity.Diagnoses:We report a female premature infant who succumbed to intracranial hemorrhage caused by medulla oblongata dysplasia.Patient concerns:The infant was born at 31 weeks gestation. The onset manifestation was symptomatic epilepsy associated with subependymal hemorrhage.Interventions:Levetiracetam and sodium valproate were administered. During the hospitalization, hydrocephalus developed and the intracranial hemorrhage aggravated.Outcomes:The infant died on day 171 after birth.Lessons:Early identification and prompt treatment should be emphasized. Clinicians should be aware of this condition, as it can potentially cause neonatal intracranial hemorrhage.

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