Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report

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Abstract

Rationale:

Tuberculous meningitis is a highly morbid, often fatal disease.

Patient concern:

We describe a case of an Italian child.

Diagnoses:

we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and paradoxical reaction with brain pseudo-abscesses.

Interventions:

The child started readily a specific therapy associated with steroids and thalidomide was introduced few month later.

Outcomes:

the patient had a favorable outcome without neurologic sequelae.

Lessons:

Despite the prompt specific anti-tubercular and adjuvant corticosteroid therapies, only the addition of thalidomide to the treatment allow to a favorable clinical outcome.

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