Comparisons of the accuracy of radiation diagnostic modalities in brain tumor: A nonrandomized, nonexperimental, cross-sectional trial

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Abstract

Tumor morphology improved sensitivity, accuracy, and specificity of the diagnosis, but all diagnostic techniques have attenuation correction issues.

To compare computed tomographic (CT), positron emission tomographic (PET), and magnetic resonance imaging (MRI) characteristics of patients with brain tumor in a Chinese setting.

A nonrandomized, nonexperimental, cross-sectional trial.

Jining No. 1 People's Hospital, China.

In total, 127 patients who had clinically confirmed a brain tumor were included in the cross-sectional study. Patients were subjected to brain CT, MRI, and PET. The tumors resected after brain surgery were subjected to morphological diagnosis. Statistical analysis of data of surgically removed tumor and that of different methods of diagnosis was performed using Wilcoxon test following Tukey–Kramer test. Spearmen correlation was performed between diagnostic modalities and in vivo morphology. Results were considered significant at 99% of confidence level.

The data of diameter and volume of tumor derived from CT (Spearman r = 0.9845 and 0.9706), and MRI (Spearman r = 0.955 and 0.2378) were failed to correlate with that of that of the surgically removed tumor. However, prediction of diameter and volume of the tumor by PET (Spearman r = 0.9922 and 0.9921) were correlated with that of the surgically removed tumor. CT and MRI were failed to quantified pituitary adenomas.

The study was recommended PET for assessment of brain tumor.

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