Primary squamous cell carcinoma of the pancreas with effective comprehensive treatment: A case report and literature review

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Abstract

Rationale:

Primary squamous cell carcinoma (SCC) of the pancreas is a rare entity since the pancreas lacks squamous cells. This condition is associated with a poor prognosis, and there is currently no optimal treatment strategy for it.

Patient concerns:

A 64-year-old female patient with a complaint of epigastric pain for 3 months was referred to our hospital.

Diagnoses:

She was finally diagnosed with primary SCC of the pancreas with lymph node metastasis on the basis of radiological and pathological findings.

Interventions:

She received chemoradiation along with targeted therapy and was provided with treatment response evaluation through PET/CT.

Outcomes:

She eventually died of tumor progression after 8 months.

Lessons:

Primary SCC of the pancreas is associated with a poor prognosis. Comprehensive therapy and proper radiologic evaluation may facilitate prolonged survival of these patients.

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