Effects of iron repletion on JOURNAL/mespex/04.02/00005768-199312000-00012/ENTITY_OV0312/v/2017-07-20T222403Z/r/image-pngO2max, endurance, and blood lactate in women

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Abstract

LaMANCA J. J. and E. M. HAYMES. Effects of iron repletion on VO2mx, endurance, and blood lactate in women. Med. Sci. Sports Exerc., Vol. 25, No. 12, pp. 1386–1392, 1993. To determine the effects of an 8-wk dietary iron supplementation (100 mg.d-1) on low plasma ferritin concentration (<20 ng.ml-1) and endurance, 20 active women (19–35 yr) were studied while performing a JOURNAL/mespex/04.02/00005768-199312000-00012/ENTITY_OV0312/v/2017-07-20T222403Z/r/image-pngO2max test and an endurance test (80% JOURNAL/mespex/04.02/00005768-199312000-00012/ENTITY_OV0312/v/2017-07-20T222403Z/r/image-pngO2max) on a cycle ergometer. Subjects were randomly placed in an iron supplement (IG) or a placebo group (PG) using a double-blind method. After treatment in the IG, ferritin levels were higher (22.5 ± 3.4 vs 14.3 ± 2.2 ng.ml-1; P < 0.05), Hb increased (12.8 ± 0.4 to 14.1 ± 0.2 g.dl-1; P < 0.05), and TIBC decreased (366.2 ± 24.8 to 293.8 ± 14.0 μg.dl-1; P < 0.05). Also after treatment the IG's JOURNAL/mespex/04.02/00005768-199312000-00012/ENTITY_OV0312/v/2017-07-20T222403Z/r/image-pngO2max was significantly greater (P <0.05) than the PG value and their postendurance blood lactate decreased (5.03 ± 0.44 to 3.85 ± 0.6 mM.1-1; P < 0.05). Endurance time to exhaustion increased 38% (37.28 ± 5.03 to 51.4 ± 7.45 min) following iron treatment; however, this change was not statistically significant. The results suggest that this level of iron supplementation can reverse mild anemia, increase JOURNAL/mespex/04.02/00005768-199312000-00012/ENTITY_OV0312/v/2017-07-20T222403Z/r/image-pngO2max, and reduce blood lactate concentration after submaximal exercise.

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