Intracellular antigens as targets for antibody based immunotherapy of malignant diseases

    loading  Checking for direct PDF access through Ovid

Abstract

This review discusses the potential use of intracellular tumor antigens as targets of antibody-based immunotherapy for the treatment of solid tumors. In addition, it describes the characteristics of the intracellular tumor antigens targeted with antibodies which have been described in the literature and have been identified in the authors' laboratory. Finally, the mechanism underlying the trafficking of the intracellular tumor antigens to the plasma membrane of tumor cells are reviewed.

Related Topics

    loading  Loading Related Articles