TRIGEMINAL-HYPOGLOSSAL SILENT PERIOD: A PONTOMEDULLARY BRAINSTEM REFLEX

    loading  Checking for direct PDF access through Ovid

Abstract

Introduction:

Animal studies have shown inhibitory connections between the sensory trigeminal nucleus and hypoglossal nucleus. I investigated whether these inhibitory projections are present in humans.

Methods:

I examined 18 healthy subjects, 2 patients with brainstem stroke, and 5 patients with multiple sclerosis using a specially designed oral stimulation and recording device.

Results:

In 16 of 18 subjects, a bilateral suppression period of tongue muscle activity after unilateral electrical stimulation of the mucosal V2 afferents was observed. The silent period started at 31.1 (SD 4.7) ms (ipsilateral) and 32.0 (SD 4.9) ms (contralateral). The mean duration of the silent period was 31.4 (SD 10.2) ms (ispilateral) and 32.5 (SD 9.8) ms (contralateral). Patients with dorsolateral pontomedullary lesions had ipsilateral absence of the silent period.

Conclusions:

This study confirms the existence of a bilateral trigeminal-hypoglossal silent period in humans. Muscle Nerve 51: 538–540, 2015

Related Topics

    loading  Loading Related Articles