The exact role of the parietal lobe in spatial cognition is controversial.One influential hypothesis proposes that it subserves spatial perception , whereas other accounts suggest that its primary role is to direct spatial movement [2,3]. For humans, it has been suggested that these functions may be divided between inferior and superior parietal lobes, respectively [2,4]. In apparent support of a purely perceptual function for the inferior parietal lobe (IPL), patients with lesions to this structure, particularly in the right hemisphere, exhibit unilateral spatial neglect (deficient awareness for the side of space opposite to that of their lesion) . Here we show that patients with right IPL lesions also have a specific difficulty in initiating leftward movements towards visual targets on the left side of space. This motor impairment was not found in neglect patients with frontal lesions, contrary to previous proposals that motor aspects of neglect are particularly associated with anterior damage [6-9]. Our results suggest that the human IPL operates as a sensorimotor interface, rather than subserving only perceptual functions.