Combining antimuscarinics shows promise for overactive bladder


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Abstract

Antimuscarinic therapy for children with overactive or neurogenic bladder is limited by its suboptimal efficacy and tolerability. New research suggests that double antimuscarinic treatment can improve continence and urodynamic parameters with an acceptable rate of adverse effects. Although the study was small and uncontrolled, it provides the impetus for larger randomized double-blind analyses.

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