Christopher J. D. Wallis is at the Division of Urology, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada; and at the Institute for Health Policy, Management & Evaluation, University of Toronto, 155 College Street, Toronto, Ontario, M5T 3M6, Canada.Raj Satkunasivam is at the Division of Urology, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada.
Checking for direct PDF access through Ovid
Understanding risk factors for prostate cancer is an important step towards personalized, risk-adapted early detection and prevention. Epidemiological studies, which are commonly used to identify risk factors, are prone to detection bias. This bias could substantially affect the observed relationship between putative risk factors and prostate cancer diagnosis.Refers to Tangen, C. M. et al. Biases in recommendations for and acceptance of prostate biopsy significantly affect assessment of prostate cancer risk factors: results from two large randomized clinical trials. J. Clin. Oncol. http://dx.doi.org/10.1200/JCO.2016.68.1965 (2016)