A case of POEMS syndrome treated by autologous hematopoietic stem-cell transplantation

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Abstract

Background

A 55-year-old woman with no remarkable medical history presented to a neurology ward with a 17-week history of rapidly progressive gait difficulties that confined her to a wheelchair.

Investigations

Electroneuromyography, immunoelectrophoresis, bone radiography, lesion-targeted bone-marrow examination, blood tests.

Diagnosis

Neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome.

Management

High-dose chemotherapy and autologous hematopoietic stem-cell transplantation.

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