Disodium pamidronate for treating severe hypercalcemia in a hemodialysis patient

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Abstract

Background

A 48-year-old man with a recent diagnosis of multiple myeloma and rapidly progressive oliguric end-stage renal disease requiring hemodialysis, presented with a serum calcium concentration of 3.4 mmol/l (13.6 mg/dl).

Investigations

Serum laboratory analysis, electroencephalogram, MRI of the brain and bone marrow, and kidney biopsies.

Diagnosis

Hypercalcemia secondary to multiple myeloma.

Management

Short-term intravenous disodium pamidronate therapy (30 mg daily) and daily monitoring of serum calcium concentration.

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