The neurobiology of the male sexual refractory period

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HIGHLIGHTSThe sexual refractory period is a sexually dimorphic phenomenon.It has long been recognized, but its mechanism is unknown.Examining the data on this phenomenon, a coherent picture begins to emerge.Despite having been recognized for many years, the mechanisms governing the male sexual refractory period (post-ejaculatory refractory period, post-ejaculatory interval) remain poorly understood. This review examines the brain and spinal areas putatively involved in this phenomenon to draw a coherent picture from the available data. It is hoped that this will reveal where further research will offer the potential for crucial insights on this topic.

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