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Unsuccessful nursing students have a great impact on nursing programs. The purpose of this study was to determine the relationships among preadmission HESI A2® (Health Education Systems, Incorporated Admission Assessment) score, science and math course grades, program completion, and NCLEX-RN® success in an associate degree nursing program using a retrospective, correlational research design. A statistically significant relationship was found between preadmission examination scores and successful NCLEX-RN passage on first attempt. Program completion had a positive correlation with preadmission science grades and HESI A2 scores.