Active microglia, sick astroglia and Alzheimer type dementias

    loading  Checking for direct PDF access through Ovid

Abstract

We propose that Alzheimer's disease is initiated by failure of axonal transport. After the neurodegeneration cascade is initiated, microglial and astroglial cells have major roles in directly and indirectly promoting self-sustaining neurodegeneration cycles. This hypothesis makes testable predictions and suggests logical therapies.

Related Topics

    loading  Loading Related Articles