PHENOTHIAZINE DEATH: AN UNUSUAL CASE REPORT


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Abstract

This paper is a case report of sudden, unexpected autopsy-negative death in a hyperactive, hospitalized patient being treated with a modified schedule of rapid tranquilization. The data of the study suggest that death was caused by phenothiazines and that phenothiazines can cause clinically significant depression of the medullary respiratory centers of the brain stem. Clinicians should monitor rate and quality of respirations as well as blood pressure closely when schedules of rapid tranquilization are implemented.

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