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One hundred two cardiac surgery patients were tested with the Minnesota Multiphasic Personality Inventory (MMPI) preoperatively and 98 of these patients (two died, two were untestable) were tested both pre- and postoperatively with the Wechsler Adult Intelligence Scale, Bender-Gestalt, and the Wechsler Memory Scale. A large number of the patients obtained preoperative “neurotic”-type MMPI profiles. Postoperative deficits in intellectual ability were slight for the group as a whole, however, there was marked within-group variance. The MMPI was not found to be useful as a predictor of postoperative intellectual changes.