Neuropsychological Profiles in Bipolar Affective Disorder and Complex Partial Seizure Disorder

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This study compared neuropsychological profiles of bipolar patients, complex partial seizure disorder patients, and normal controls. Complex partial seizure patients performed worse than bipolar patients or normal controls in one of five neuropsychological domains examined in an analysis of variance (focusing–execution) and on delayed verbal recall; they performed worse than bipolar patients in the verbal domain. Bipolar patients performed worse than normal controls in focusing–execution and showed clinical elevation on one scale of the Minnesota Multiphasic Personality Inventory. The data suggest both similarities and differences in the neuropsychological profiles of patients with bipolar affective disorder and patients with complex partial seizure disorder.

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