Current Opinion in Neurology. 9(3):159–164, JUNE 1996
PMID: 8839606
Issn Print: 1350-7540
Publication Date: June 1996
Animal models of demyelination
M. Njenga;Moses Rodriguez;
+ Author Information
Departments of Immunology and Neurology. Mayo Clinic, Rochester. Minnesota, USA
Abstract
In the past year, animal studies on central nervous system demyelination have focused on therapeutic strategies and the functional characterization of T-cells, cytokines, and adhesion molecules. Significant progress has been realized in the treatment of animals with experimentally induced demyelinating disease using glial cell transplants, autoantibodies, cytokines, growth factors, and by inhibiting adhesion molecules and cytokines. In this review, we summarize the important contributions made in those respective areas.
