Endovascular Treatment of 346 Middle Cerebral Artery Aneurysms: Results of a 16-Year Single-Center Experience

    loading  Checking for direct PDF access through Ovid

Abstract

BACKGROUND:

The endovascular treatment of middle cerebral artery (MCA) aneurysms has been controversial because of the frequency of complex anatomy and the relative ease of surgical clipping in this location.

OBJECTIVE:

To present a large single-center experience with the endovascular treatment of MCA aneurysms.

METHODS:

The neurointerventional database at our institution was reviewed for all endovascular treatments of MCA aneurysms. Demographics, aneurysm characteristics, treatment modality, intraprocedural hemorrhagic and thromboembolic events, 30-day neurological events, and follow-up angiographic studies were recorded.

RESULTS:

From December 1996 to April 2013, 292 patients underwent endovascular treatment of 346 MCA aneurysms. Of these, 341 (98.6%) were successfully completed. Balloon neck remodeling was used in 230 procedures (66.5%). Ninety-five procedures (27.4%) were for ruptured aneurysms. The rate of intraprocedural hemorrhage was 2.6% (9 of 346). The overall rate of intraprocedural thromboembolic events was 13.6% (47 of 346), significantly more common in patients with acute subarachnoid hemorrhage (27.4%; P < .001). The 30-day major (modified Rankin Scale score > 2) neurological event rate was 2.9% (10 of 346), significantly more common in patients with subarachnoid hemorrhage (8.4%) compared with those without (0.8%; P < .001). The rate of complete or near-complete aneurysm occlusion at was 90.6% ≥ 6 months and 91.8% at ≥ 2 years, with an average of 24 months of follow-up available for 247 procedures.

CONCLUSION:

Endovascular treatment of MCA aneurysms can be safe and effective. However, it is associated with a high asymptomatic thromboembolic event rate that is more frequent in the setting of acute subarachnoid hemorrhage.

ABBREVIATIONS:

ISAT, International Subarachnoid Aneurysm Trial

ABBREVIATIONS:

MCA, middle cerebral artery

ABBREVIATIONS:

mRS, modified Rankin Scale

ABBREVIATIONS:

SAH, subarachnoid hemorrhage

ABBREVIATIONS:

TIA, transient ischemic attack

Related Topics

    loading  Loading Related Articles