No Evidence Supporting Coenzyme Q10 Use in Parkinson's Disease

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Abstract

SYNOPSIS:

This large, randomized Phase 3 clinical trial of high-dose coenzyme Q10 failed to show any neuroprotective benefit in early Parkinson's disease.

SOURCE:

Parkinson Study Group QE3 Investigators. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: No evidence of benefit. JAMA Neurol 2014;71:543-552.

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