Medication for Acute Low Back — A Randomized Clinical Trial

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SYNOPSIS: In a trial comparing naproxyn alone to combinations with cyclobenzaprine or oxycodone/acetaminophen in patients with acute low back pain, there was no difference in outcome after 1 week.

SOURCE: Friedman B, et al. Naproxyn with cyclobenzaprine, oxycodone/acetaminophen, or placebo for treating acute low back pain. A randomized clinical trial. JAMA 2015;314:1572-1580.

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