Extensive Postradiation Ocular and Diffuse Cranial Neuromyotonia Mimicking Myasthenia Gravis

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Abstract

Background:

Ocular neuromyotonia is a rare, but well-recognized, complication of cranial irradiation.

Case Report:

Using figures and videos, we report a 52-year-old man with extensive ocular, brainstem, and lower cranial nerve neuromyotonia postradiation therapy for a fourth ventricle glioma who, in the context of an apparently positive edrophonium test, was initially misdiagnosed with myasthenia gravis.

Conclusions:

This is the first case of postirradiation neuromyotonia to be reported with such extensive cranial nerve and brainstem involvement.

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