Extensive Postradiation Ocular and Diffuse Cranial Neuromyotonia Mimicking Myasthenia Gravis

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Ocular neuromyotonia is a rare, but well-recognized, complication of cranial irradiation.

Case Report:

Using figures and videos, we report a 52-year-old man with extensive ocular, brainstem, and lower cranial nerve neuromyotonia postradiation therapy for a fourth ventricle glioma who, in the context of an apparently positive edrophonium test, was initially misdiagnosed with myasthenia gravis.


This is the first case of postirradiation neuromyotonia to be reported with such extensive cranial nerve and brainstem involvement.

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