HYPERTENSION: Definition of pulmonary hypertension challenged?

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The current definition of pulmonary hypertension (PH) is based on resting mean pulmonary arterial pressure (mPAP) ≥25 mmHg; however, analysis of long-term follow-up data now reveals increased mortality even with mPAP ≥19 mmHg. Do we need to modify the definition of PH, and what are the implications for clinical practice?

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