Oliver Soehnlein and Carlos Silvestre-Roig are at the Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich, Pettenkoferstrasse 9, 80336 Munich, Germany; and the German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany. Oliver Soehnlein is also at the Department of Physiology and Pharmacology, Karolinska Institutet, von Eulers Väg 8, 17177 Stockholm, Sweden.
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Contradictory results in animal atherosclerosis studies might partly explain limited translational efficacy, and also undermine the confidence of funding agencies, politicians, and the public in scientists and their research. A new guideline paper provides recommendations aimed at standardization of animal atherosclerosis studies to improve the reproducibility of this research.Refers to Daugherty, A. et al. Recommendation on design, execution, and reporting of animal atherosclerosis studies: a scientific statement from the American Heart Association. Circ. Res.http://dx.doi.org/10.1161/RES.0000000000000169 (2017)