DYSLIPIDAEMIA: Lysosomal acid lipase deficiency—a cautious leap forward

    loading  Checking for direct PDF access through Ovid


Lysosomal acid lipase deficiency can lead to liver failure and early death. A recently published placebo-controlled trial shows that enzyme-replacement therapy improves plasma levels of lipids and aminotransferases, and reduces liver fat content. However, the effect on clinical end points and an appropriate indication for treatment remain to be established.

Related Topics

    loading  Loading Related Articles