BONE DISEASES: Romosozumab — on track or derailed?

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Abstract

Romosozumab, a recently developed sclerostin inhibitor, stimulates bone formation and inhibits bone resorption, thereby markedly increasing bone mass and reducing fracture risk. But will a red flag regarding possible adverse cardiovascular events derail this promising new drug for osteoporosis?

Refers to Saag, K. G. et al. Romosozumab or alendronate for fracture prevention in women with osteoporosis. N. Engl. J. Med.http://dx.doi.org/10.1056/NEJMoa1708322 (2017)

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