The role of group B coxsackieviruses (CVB) in the pathogenesis of type 1 diabetes mellitus (T1DM) remains controversial. A recent report by Stone et al. showed that a CVB1 based vaccine can protect against both CVB1 infection and CVB1-induced T1DM in mouse models. This tool could help to elucidate the relationship between CVB and T1DM.
Refers to Stone, V. M. et al. A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type diabetes. Diabetologia61, 476-481 (2018)