Treatment of chronic hepatitis C in a slow responder: a case for extended therapy

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Abstract

Background.

A 49-year-old white man presented to his primary-care clinic with fatigue and poor concentration. He had an enlarged liver with a minimally tender edge and was subsequently referred to our liver clinic.

Investigations.

Physical examination, laboratory investigations (including tests for HCV-RNA, antibodies to hepatitis B surface and core antigens, and HBV-DNA), and liver biopsy.

Diagnosis.

The patient had chronic hepatitis C infection and was a slow responder to treatment.

Management.

Administration of pegylated interferon α2b plus ribavirin for 72 weeks. Escitalopram was given to manage his depression.

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