TRANSPLANTATION: Alloantibodies in simultaneous liver-kidney transplantation

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O'Leary et al. report that the presence of anti-HLA antibodies at the time of simultaneous liver-kidney transplantation is associated with allograft dysfunction and shortened organ and patient survival. Preformed class I alloantibodies were eliminated after transplantation, whereas class II donor-specific antibodies persisted and were associated with poor outcomes.

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