Elad I. Levy is in the Departments of Neurosurgery and Radiology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 100 High Street, Suite B4, Buffalo, New York 14203, USA.Maxim Mokin is in the Departments of Neurology and Neurosurgery, University of South Florida College of Medicine, 2 Tampa General Circle, Tampa, Florida 33606, USA.
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Two studies have shown no added benefit of intravenous thrombolysis in patients with acute stroke who are treated with mechanical thrombectomy. We review the importance and interpretation of these findings, compare them to the current guidelines on stroke thrombectomy, and discuss how these studies can change our daily clinical practice.Refers to Abilleira, S. et al. Outcomes after direct thrombectomy or combined intravenous and endovascular treatment are not different. Stroke 48, 375-378 (2017) | Coutinho, J. M. et al. Combined intravenous thrombolysis and thrombectomy versus thrombectomy alone for acute ischaemic stroke: a pooled analysis of the SWIFT and STAR Studies. JAMA Neurol.http://dx.doi.org/10.1001/jamaneurol.2016.5374 (2017)