SCREENING: Guidelines for antiphospholipid antibody detection

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Abstract

The reproducibility and reliability of ELISA assays used to detect autoantibodies that recognize cardiolipin or β2-glycoprotein I remain unacceptable, which can complicate the diagnosis of antiphospholipid syndrome. Now, much needed international consensus guidelines have been proposed for the development and use of these diagnostic tests, which should improve their performance.

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