Radiographic joint-space width is the standard structural outcome for trials in knee osteoarthritis (OA), but MRI provides comprehensive 3D insights into the multi-tissue pathology of OA and could provide a superior means of monitoring disease progression and response to treatment. A new study highlights bone as an imaging biomarker.
Refers to Barr, A. J. et al. The relationship between three-dimensional knee MRI bone shape and total knee replacement — a case-control study: data from the Osteoarthritis Initiative. Rheumatology (Oxford) doi:10.1093/rheumatology/kew191 (2016)