Acquired autoimmune thrombotic thrombocytopenic purpura

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Abstract

Acquired autoimmune thrombotic thrombocytopenic purpura (TTP)—the most common form of TTP—is a life-threatening hematologic disease characterized by hemolytic anemia and thrombocytopenia. Acquired autoimmune TTP can cause signs and symptoms of neurologic and other organ involvement, with mortality approaching 90% if the disease is not promptly recognized and treated. Since the introduction of plasma exchange in 1991, the acquired autoimmune TTP survival rate has increased to 78%.

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