Ovarian cancer is a major health concern for women. Women are often diagnosed late in the course of the disease, making the mortality rate high. Currently, screening methods for ovarian cancer are limited and, therefore, prevention methods remain an area of focus for researchers. Recent research has examined the salpingectomy and tubal ligation/sterilization as a prevention method for ovarian cancer. This column takes a second look at two recent research studies that examine salpingectomy and tubal ligation/sterilization as a method of ovarian cancer risk reduction.