Hormonal Contraception and Glioma: Is There Reason for Concern?

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SYNOPSIS: A large case-control study using the Danish National database found a slight increase in the risk of glioma in ever-users of hormonal contraception, which increased with duration of use. Users of progestin-only methods were at higher risk. However, these findings should not influence clinical practice or perception of contraceptive safety.

SOURCE: Andersen L, et al. Hormonal contraceptive use and risk of glioma among younger women: A nationwide case-control study. Br J Clin Pharmacol 2014; Oct 26. doi: 10.1111/bcp.12535 [Epub ahead of print].

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