Recent studies using data from the California Prenatal Screening Program show that standard screening protocols, which combine first trimester ultrasound and biochemistry with second trimester biochemistry, has a very acceptable detection rate and outperforms NIPT in cost-effectiveness in low-risk patients.SOURCES:
Baer RJ, et al. Detection rates for aneuploidy by first trimester and second trimester screening. Obstet Gynecol 2015;126:753-759.SOURCES:
Kaimal AJ, et al. Prenatal testing in the genomic age: Clinical outcomes, quality of life, and costs. Obstet Gynecol 2015;126:737-746.