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(Acta Obstet Gynecol Scand. 2016;95:724–734)Fibroids are benign tumors of the female reproductive tract that are often treated with myomectomy. However, 1 potential adverse outcome of this procedure is an increased risk of uterine rupture during a subsequent pregnancy. The literature reports this risk to be around 0.7% to 1%. Uterine rupture is known to be associated with a high risk of morbidity and mortality for both the mother and the fetus. The objective of this study was to assess the occurrence of uterine rupture and the related risks in women who underwent a trial of labor after having had a myomectomy. This study involved a review of all the literature published on this topic and included all cohort studies with at least five cases of pregnancy after myomectomy.