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(Anesthesiology. 2016;125(2):295–303)According to airway management guidelines, emergency cricothyrotomy is recommended in “cannot-intubate, cannot-ventilate” situations. Earlier studies showed that surgical cricothyrotomy had 90% success rates, while nonsurgical cricothyrotomy had success rates of only 65%. The present study aimed to evaluate the efficacy and safety of 3 commonly used cricothyrotomy techniques, namely the Melker set, the QuickTrach II set, and the surgical technique, performed in cadavers by surgical airway–naive medical personnel.