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(J Clin Anesth. 2016;35:54–57)During labor and delivery, there are many options available for pain relief, and the inhalation of nitrous oxide (N2O) is one of the methods that is gaining popularity in the United States. However, the effect of N2O availability on the utilization patterns of other forms of labor analgesia such as neuraxial labor analgesia (especially in large American hospital settings) has not been studied. The objective of this study was to examine how the use of N2O during labor and delivery would influence the pattern of neuraxial labor analgesia.