When spinal anesthesia is administered for cesarean delivery, maternal hypotension occurs in ∼70% of women, due primarily to decreases in systemic vascular resistance and cardiac output. This hypotension can be detrimental to the fetus. Therefore, the ability to identify patients at increased risk for developing spinal-induced hypotension and then implementing preventive strategies in these women could be clinically beneficial. The main purpose of this prospective observational study was to investigate the effectiveness of certain transthoracic echocardiographic (TTE) measurements to determine a patient’s intravascular volume and predict her risk of developing hypotension resulting from spinal anesthesia for cesarean delivery. In addition, they aimed to determine whether certain subgroups at increased risk for hypotension could be identified with this point-of-care echocardiographic examination.