APPEARANCE OF MATERNAL ANTI-JKa ANTIBODY FOLLOWING INTRAUTERINE TRANSFUSIONS AND AMNIOCENTESIS

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Abstract

A case is presented that suggests that intrauterine transfusion carries the risk of sensitization to red cell antigens other than Rh0+ In this case intrauterine transfusions of Jk11 positive red cells were followed by the appearance in the mother's serum of anti-Jk, an antibody known to cause hemolytic disease of the newborn. The use of the mother as a donor of red cells for her fetus will circumvent the problem of further maternal sensitization.

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